Friday, June 19, 2020

Data!

Having a large amount of data in your hands sounds like a great end to a project in the beginning. By the end, you realize that it was really only a beginning and not such a great one at that. It is like you went to a yard sale and brought all this junk for free. At that time it sounded like a great idea. Now you have no idea what to do with it.

As you begin your analysis you start getting these ‘very significant’ changes, large sets of genes are heaving up into a wave and falling back down, or dipping down into the abyss and then pulling themselves up in a joint effort! Wow! There you stand like Columbus, at the helm of Santa Maria, about to discover the new land, full of possibilities, new stories, new animals, new riches. And then suddenly there emerges from the forest a man, then another and then another with that ‘been-here-done-it’ look. They have found, killed the animals, domesticated the plants, built their huts and tamed the rivers. And you gingerly step into the land and try to edge your way between them into the thick forest knowing you are just another traveller, just another of those wandering species that goes about disrupting the homeostasis. As you cut away the heavy loaded branches blocking your path and push the undergrowth out of the way and scare the small animals off as you take each step, you are hoping that there is something left in this forest, something for you to find, discover, for the first time and hold it aloft like the Statue of Liberty and shout or rather mutter hesitantly that here, I have found a plant, looks a bit like the ivy, is just less poisonous, something like the bird of paradise, just a little less flamboyant, but here it is!

Photo by Francesco Ungaro from Pexels

Anxious about anxiety

Imagine somebody has signed you up for a skydiving experience. You are standing inside the aircraft. The hatch is open. Your guide is telling you to go ahead, jump. Nothing to worry, they will take care of you. All the others have taken the plunge. There is a yawning emptiness in the pit of your stomach. Your heart is racing; your throat is dry. You are barely standing. You take a deep breath, a tremulous smile. Yes, you can do it. You take that step forward. No! You cannot do it. You shrink back. Do they think you are crazy to rely on their words? What if the parachute does not open? What if you can't breathe? What if you lose consciousness? All manner of horrors are possible. Voices are screaming around you. You are a coward! Everyone can do it, what's special about you? You shrink into yourself. You are hyperventilating; eyes darting back and forth. What if one of these monsters pushes you? You feel totally powerless. You are losing control. My daughter goes through this crisis every single morning when we reach the gates of the school.

 

For the last two years I have watched my daughter go through this torture, refusing to go to school, time and again. Sometimes it is a couple of days, sometimes a week, at the worst, a whole fortnight. I have battled my feelings swinging from sympathy to frustration to anger. I have vacillated between giving her a break, cajoling, bribing, threatening, shaming and I am sad to say, hitting. They have all worked at times, forcing her into the school against her better sense, but many times not. I have marvelled at her stubbornness and the power of her refusal. She just wouldn’t bend, be it threats, shaming, authority or love. The refusal turned to stomachache, headache, nausea, fever, you name it. Every day she would turn up at the school clinic with a complaint and I would regularly get calls to pick her up from school. Then the clinic staff started shouting at her for making things up, ‘there is nothing the matter with you!’ One day they sent her to the headmistress who told her kids don't have headaches and sent her back to class. Being a huge school, with a large student strength, perhaps made them ill equipped to deal with the out of ordinary.

 

Through this all, I industriously Googled® for answers. The keyword that jumped out at me repeatedly was, anxiety. Anxiety, as defined by the Merriam-Webster dictionary, is an apprehensive uneasiness or nervousness usually over an impending or anticipated ill. It is an ever-present emotion for most people and it protects us from reckless behaviour. But sometimes the amygdala, a deep-seated organ within the brain which controls our emotions, becomes overactive. Then, the mind inflates the spectre of the ‘impending ill’ interfering with our ability to function in the society. And there you have an anxiety disorder, panic attacks and in some cases, phobia.

 

I discovered that regular complaints about apparently unrelated physical problems that do not seem to go away with symptomatic treatment is a classic warning sign of anxiety. I wondered if the professionals in the school clinic had not learned this in their medical training, or simply did not care. The scientist in me started looking for triggers for this anxiety. I tried placebo treatment for her symptoms. We 'scientifically' changed her diet, gave her vitamin syrups with magical properties. And slowly things settled. She started attending class, enjoying the daily banter with her classmates, loving her teachers. She identified 'good’ teachers who took her troubles seriously and helped her and 'bad' teachers who did not believe her and scolded her.

 

The PTMs and discussions with her teachers gave me the impression of well-meaning but overburdened teachers. They were compassionate about her absenteeism but more worried about the effect it was having on her academic performance. With each class nearing a strength of 40, and multiple classes to teach, it was not surprising that they didn’t have much time to think deeply about each student. No time to think beyond academics, no time to discover what other talents and strengths the kids might have. The system was designed to select academic high-achievers and extroverted talents; others were invisible. 

 

I decided that a move would be good for her in the long run, although it might turn out to be traumatic at the moment. I looked for a smaller strength school, where they could work with the kids, where they respected other talents beyond academics, where they took the time to discover hidden talents and nurture their strengths. Although such paragons of educational virtue are hard to come by, I did manage to move her to a smaller school with small class strength and a little more respect for non-academic achievements.

 

But soon after the excitement of new uniform and new books was over, she began refusing to go to school again. Now I knew it was not school specific. It put to rest that unspoken fear that had gnawed at my mind that there was something that happened in the previous school that had triggered her fear. The response of this school was dramatically different. After a few days of her not making it to school, I was called in by the teacher. The principal madam talked to me. I had a meeting with the school counsellor and my daughter’s class teacher to discuss what the triggers might be and how they can help. She stood outside the meeting room the whole time, right in front of the principals' office and cried, and nobody shouted at her! My self-doubt and unsureness at having moved schools was put to rest.

 

I decided it was time to bite the bullet and visit a mental health professional. The decision was not easy. Whatever science you know, however progressive your views may be, mental health problem still meant ‘an inability to control our minds’. A sign of weakness. An acknowledgement of defeat. But all my research, reading and discussions with my scientist colleagues convinced me that my daughter is suffering

and I needed to get help. The first visit turned out to be more of a therapy for me. I talked for an hour about my daughter. I discovered how much I loved her, how much I worried about her and how many dreams and fears I carried around with me. Then came the psychiatric evaluation. Again, it was a step that I would rather not have taken, but in for a penny in for a pound. Instead of the veiled discussions with parents and sugar coating for the child, the psychiatrist sat us both down and talked straight to my 9-year-old daughter. He discussed her complaints. He drew a graph! A graph of anxiety vs performance to explain the issue to her. She sat and listened to him, sometimes nodding sometimes disagreeing! I guess that is what we all want first and foremost, respect. She started therapy.

 

I was going through my personal unofficial not-paid-for therapy. I learned that when she is anxious what she needs around her is a calm presence. Not a stressed-out soul who extrapolates 20 years ahead and who foresees a bleak future projected from her every current action. I have realized that as a parent it is the fear of the future that drives us to our actions; the scolding, the pushing and pressurizing, the nagging, the berating. I discovered that if I just provide a safe environment for her, where she doesn’t have to constantly keep looking over her shoulder, where she doesn’t have to second guess if mom is lying and where she doesn’t have to constantly feel she is not measuring up, then she will take that tentative step forward, take that small risk, and buoyed by the success, take that next step… The trick is to ‘just chill mom’ as she says.

 

But then while we are still on this journey of self-discovery, my daughter and I…the world turned upside down. Today there is not a person who is not anxious; fearful of an invisible but very real virus, fearful of not finding a hospital bed, fearful of finding one but only to die on it alone.

 

As the world struggles to fight, then hide from and then come to terms with this new enemy, schools have shut. Kids, and adults, have been cooped up within four walls for days at end. My little one was very excited about home schooling, when it all began. But two months of it and now all she wants is to go back to school. But what would schools be like in post-COVID era, one wonders. What new monsters will be lurking around the corner? What new terrors await us?


This article appeared in The Indian Express on June 11, 2020 

Wednesday, June 3, 2020

Putting out to pasture

20100604 used to be my password. The day I started in my new role; as an independent scientist. It was a momentous day. A place I had dreamed to be and then arrived. So it felt then. That was 10 years ago!

The truth was that I was quite unprepared. I, in fact, had no clue what being a scientist entailed. All the ‘un-scientist like’ things I had to do. Lots and lots of paperwork, lots of learning of administrative lingo, learning the rules and how to wiggle through them. Lots of arguing with colleagues, shouting in corridors, losing my temper (definitely not part of my routine as a pre-PI), fuming alone in my office, taking the simmering dissatisfaction and anger home. Then learning to lower the heat slowly, finding my own comfortable temperature on the settings, learning the ropes of dealing with the director, senior colleagues, equals, juniors (oh the invisible hierarchy!). 


Yes, I was quite unprepared for the students who did not understand the point of controls. Students who had no eye for detail. No idea on how to deal with students having babies, having break-ups and breakdowns, having spats and chronic incompatibilities, having self-doubt or no doubt at all! The anger and frustration (at what I can’t now remember) that left me shaking, sweat beading on my forehead and afraid of having a breakdown myself. Then slowly learning to let it all wash over me, watching my students learn to take my out-of-the-blue ideas (or counter-ideas) and then walk away blithely without paying any heed, discovering my students discover the joy of science and process of it. Reaching that homeostasis that worked for me; perhaps for them too.


I was also quite unprepared for the tangents that threw me around. The trouble with the idea of unfettered freedom (such a thing does not exist). The 9 students and the 9 different fields we explored! The lack of space in my brain for so many compartments. The fits and starts that each project brought and took away with it. The pace at which you need to switch gears! The realization that what I called multitasking was not it at all! 


However, as we say in papers, there was also enjoying the banter of colleagues in the lunchroom, cracking wisecracks and then suffering for it on WhatsApp groups, chilling a wee bit uncomfortably on the lab trips and picnics, relaxing on those evenings with alcohol with colleagues across the country at conferences. There was also the sheer joy of sitting back on my comfy chair and gorging on beautiful data brought in by students who worked hard at it, now displayed on my 26” HD screen (and not feeling any guilt for it). 


Yes, it has been 10 years. Longer than I have ever stayed in one place  physically or mentally, ever in my life, be it school, college, PhD or post-doc. It also has been 70 days that I have stayed at home. Longer than I have ever stayed home since I was six years old! 40 years. 10 years. 70 days. Too many numbers. Too much inactivity. Too much social distancing. Too much time to think (and stress and hyperventilate too). It is definitely time to move a bit, if not in body, then certainly in mind. Feet are tied down, but the mind is free to wander. Time for some new challenges, some new pastures. Let us nibble away to the far end of the field and see how the grass tastes there.  

They don’t mind/ Don’t mind them

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