Having a large amount of data in your hands sounds like a great end to a project in the beginning. By the end, you realize that it was really only a beginning and not such a great one at that. It is like you went to a yard sale and brought all this junk for free. At that time it sounded like a great idea. Now you have no idea what to do with it. As you begin your analysis you start getting these ‘very significant’ changes, large sets of genes are heaving up into a wave and falling back down, or dipping down into the abyss and then pulling themselves up in a joint effort! Wow! There you stand like Columbus, at the helm of Santa Maria, about to discover the new land, full of possibilities, new stories, new animals, new riches. And then suddenly there emerges from the forest a man, then another and then another with that ‘been-here-done-it’ look. They have found, killed the animals, domesticated the plants, built their huts and tamed the rivers. And you gingerly step into the land and try...